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For Research Use Only — Not for Human ConsumptionFree discreet shipping on orders over $200Third-party COA available on every batch
Batch · RV-SMX-2344
Semax (ACTH(4–10) Fragment Analog) research peptide — 10 mg, 99% purity, batch RV-SMX-2344

Cognitive & Focus Research

Semax

ACTH(4–10) Fragment Analog

10 mg99% purityHPLC verified

A synthetic ACTH(4–10) fragment peptide studied in neurotrophic and neuroprotective research models.

What is Semax?

Semax is ACTH(4-10) with a Pro-Gly-Pro tail appended to the C-terminus, an extension that slows enzymatic degradation while leaving out the corticotropic activity of the parent hormone. It turns up most often in BDNF and TrkB expression work, where neurotrophic signaling is the measured endpoint. Comparative studies frequently pair it with other ACTH-fragment analogs such as Adamax.

Research context

  • Neurotrophic signaling
  • BDNF expression
  • Cognitive models

Certificate in queue

This lot is with our third-party laboratory. Its certificate will be published here and on the COA lookup as soon as testing completes.

How every batch is tested

$56

$5.60 per mg

1

Dispatched within 24 hours, Monday to Friday, in discreet, unmarked packaging. Free shipping over $200 — $144 away.

COA match guarantee — if the vial you receive does not match the certificate published for its batch, we replace or refund it. Unopened vials in original packaging can be returned within 14 days of delivery.

A batch that misses specification is not listed and is not shipped. We publish every result we commission, including the ones that send a batch back.

Chromatogram and mass-spectrometry data for this compound are available on request.

For Research Use Only — Not for Human Consumption.

Specifications

Format
Lyophilized powder, sealed vial
Strength
10 mg
Purity
99% minimum, third-party verified
Testing
Third-party HPLC and mass spectrometry, per batch
Batch
RV-SMX-2344
Storage
Store lyophilized at -20 °C, protected from light and moisture. Refrigerate after reconstitution.
Handling
Reconstitute with bacteriostatic water in a controlled laboratory setting; swirl gently rather than shaking to preserve peptide structure.
Shipping
Discreet, unmarked packaging. Ships within 24 hours.
Intended use
Laboratory and in-vitro research use only. Not for human or veterinary consumption.
View Certificate of Analysis — RV-SMX-2344
Analytical Method

Four checks stand between synthesis and a listing.

Every lot in this catalog clears the same sequence. The dates below belong to batch GLP3-10-2026-01 an example of a released lot. Certificates for other products are added as testing completes.

  1. 01

    Synthesis and fill

    Lyophilized to specification and sealed under controlled conditions, one lot at a time.

    Lot GLP3-10-2026-01

  2. 02

    Chromatographic purity

    RP-HPLC with UV detection at 220 nm — the peptide-bond absorbance, so every residue in the sequence contributes to the signal. Release specification ≥ 98.0%.

    Result 99.4%

  3. 03

    Identity confirmation

    LC-MS (ESI) measures the molecular mass of the eluting species against the theoretical mass of the intended sequence. A lot can be pure and still be the wrong peptide; running both methods closes that gap.

    Confirmed

  4. 04

    Release

    Purity, identity, appearance, peptide content, water, acetate and endotoxins all within specification. Released for sale.

    Tested 2026-07-28

When a batch does not clear

It is not listed and it is not shipped. We publish every result we commission, including the ones that send a batch back. A batch earns a product page only after identity and purity have both passed.

Analytes on the record

  • HPLC Purity≥ 98.0%
  • Mass SpectrometryMatches Structure

Chromatographic purity and peptide content answer different questions. Purity is the share of peptide-related material that is the target sequence. Peptide content is how much of the vial's mass is peptide at all, the remainder being acetate counterion and residual water — a normal lyophilized acetate salt, not a discrepancy.

Analysis is performed by JanoShield Analytical, an independent laboratory with no commercial interest in the result.

For Research Use Only — Not for Human Consumption.

Common questions

What is Semax?

Semax is ACTH(4-10) with a Pro-Gly-Pro tail appended to the C-terminus, an extension that slows enzymatic degradation while leaving out the corticotropic activity of the parent hormone. It turns up most often in BDNF and TrkB expression work, where neurotrophic signaling is the measured endpoint. Comparative studies frequently pair it with other ACTH-fragment analogs such as Adamax.

How is Semax purity verified?

Every lot is assayed by third-party hplc and mass spectrometry, per batch: RP-HPLC at 220 nm establishes chromatographic purity against a 99% release specification, and LC-MS confirms molecular identity against the reference mass. The batch currently shipping is RV-SMX-2344, and its full certificate — including methods, specifications, measured results, and the testing laboratory — is published at https://rovapeptides.com/coas/RV-SMX-2344.

How should Semax be stored and handled?

Lyophilized powder, sealed vial. Store lyophilized at -20 °C, protected from light and moisture. Refrigerate after reconstitution. Reconstitute with bacteriostatic water in a controlled laboratory setting; swirl gently rather than shaking to preserve peptide structure.

What strengths of Semax are available?

Semax is supplied in 10 mg. Each presentation is filled from a tested lot and ships with its own batch number, so the certificate you retrieve always corresponds to the vial in your hand.

Is Semax intended for human use?

No. Semax is supplied strictly for laboratory and in-vitro research use. It is not intended for human or veterinary consumption, diagnostic use, or therapeutic use, and RovaPeptides provides no dosing, protocol, or usage guidance.

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